Using the Substances of Concern (SoC) Data Tables
Applicability.  Information, guidance and requirements found in these tables are applicable to substances associated with products and services procured for NIH mission activities and NIH owned or operated facilities.  This includes products and services procured directly by NIH and indirectly through its contractors.
Status of Data Development and Review.  All data in the tables should be considered provisional.  The tables, data structure and data sets are in the early phases of development and the many data fields that have not been populated with data currently display the words “No data”.  Generally applicable data for the chemical group listings and detailed information on specific substances in the groups will be developed and posted on this website as time and resources permit.  Priority may be assigned to groups and substances that have the highest level of use in facilities and mission activities, or present the greatest potential impacts on these activities.  All groups of substances intended for inclusion in the first interim listing of SoCs are now shown on this website.
Updating. The DEP will update SoC listings and information as needed.  The most recent listings and information will be posted on the NIH Environmental Management System website .  Dates of the most recent update will be indicated at the top of the list, and applicable SoC data tables.
Peer Review.   The data on this website has not been subjected to a peer review process.  Where available for specific substances direct links to the TOXNET Hazardous Substance Data Base (HSDB) have been provided in the data tables.  The HSDB contains extensive peer reviewed data sets and information.
Listing Format.  Substances will be arranged in groupings based on functionality e.g., flame retardants or by type of chemical.  A list of groups that comprise the Interim SoC List may be found in the tab titled Provisional SoC Data Tables.  We are currently building data sets for each group listing and specific substances to be included in each group. In the first data tables the words “No data” displayed in many fields indicates that we have not populated the field with data.  It also serves as a placeholder inserted to allow machine readers for the visually impaired to operate.
Searching Methods.
Information on groups of substances and specific substances may be found by using the tab titled Provisional SoC Data Tables, which will display a list of groups in alphabetical order. Clicking a group name will display a table with general information about the group, followed by a list of the Substances of Concern currently included in the group.  Clicking on a substance name in the list will take the reader directly to a table with information about the specific substance.  Readers can also scroll down the page to find the tables for specific substances.
The “Text Search” button on the home page or the “Search” tab on the top navigation bar can also be used to perform a key word search on the website.  Text searching can be used to find key words, chemical names, uses of substances etc.
Explanation of Tables.  Tables for each group of and specific substances contain the following information elements:
Group Name.  A generic name describing substances in the group usually based on the types of chemical compounds in it and, in some cases by their common use e.g., fire retardants.
Primary Hazard Listing Criteria.  These are the primary risks posed by chemicals in the group that meet one or more Substances of Concern listing criteria.  They are not intended to be complete listings of all hazards and risks posed and may not be applicable to all substances in the group.
General Uses.  The section provides a general description of the general uses or emissions of substances in the group.  Additional information on specific, mission related uses may be available in the table listings for specific substances in the group.
Reduction Strategies.  This section provides general guidance focused on procurement related methods to reduce hazards and risks associated with this group of substances.  Additional information on alternatives and strategies for reducing use may be found in the data tables for specific substances included in the listed group.
Current Procurement Restrictions.  This section provides information on bans and other procurement restrictions established by regulatory agencies, NIH policies and the NEMS.  Additional information on restrictions may be found in the data tables for specific substances included in the group.
NIH Disposal Requirements.  This provides guidance and requirements for managing products containing or emitting SoCs at the end of their useful life.  In this section the term Hazardous Waste means substances or products that may be regulated as hazardous waste by the EPA or states.  Federal and state laws and NIH pollution prevention plans require procurement of SoCs and products that are regulated as Hazardous Waste upon disposal to be minimized.  The term Chemical Waste includes all Hazardous Wastes and other chemicals and items required by NIH to be managed following requirements for Chemical Waste.  Examples of Chemical Wastes and management requirements are presented in the NIH Waste Disposal Guide.  A pure, unused SoC may require management as Hazardous or Chemical Waste if discarded whereas some used SoCs and products and formulations containing an SoC may not.  It is the responsibility of the person generating the wastes to ensure that they are properly identified and disposed of. Questions about management of these wastes at NIH facilities should be directed to the DEP at 301-496-7990 or e-mailed to
References.  References generally applicable to the group of substances are listed here.
These tables are intended provide examples of specific substances included in the group.  Tables may not be provided for all substances in the group that meet listing criteria.
Substance Name.  A common or preferred name for the substance is shown here.
Synonyms.  Commonly used synonyms are listed here.  This is not intended to be a complete listing of synonyms.
CAS RN.  CAS Registry Numbers (CASRNs) are unique identifiers assigned to every specific chemical substance appearing in the open scientific literature by the Chemical Abstract Service (CAS), a function of the American Chemical Society (ACS). CAS Registry Number is a registered trademark of the ACS.
Uses at NIH.  Examples of common and specific uses of a substance in NIH facilities and mission activities are listed here.
Alternatives and Reduction Strategies.  This section provides information on known alternatives, reduction strategies, bans and other procurement restrictions by regulatory agencies and the NEMS for substances as they are used by NIH. Specific NEMS restrictions may be developed as more comparative toxicology data on products containing SoCs and alternatives becomes available.  Data included here focuses on alternatives and strategies that can be implemented by purchasing controls.
References.  References applicable to the specific substance and its uses are posted here.  Hyperlinks to applicable reference files on the substance on the Hazardous Substance Data Base will appear here.
Data Needs.  Information on uses and alternatives for products containing or emitting SoCs in biomedical research applications will be sought for inclusion in databases supporting this effort.  Investigators are encouraged to provide this data to the DEP.  At the present time we are not able to use or post information on brand names, proprietary information and claims, commercial sources etc.  Information provided should be generic and preferably supported by citations to peer reviewed literature.
Contact Information.  Questions, comments, recommendations for list corrections and additions are welcome.  Please submit these to the Environmental Protection Division at 301-496-7990 or email to